INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF

The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and thus, they are useful for the treatment and prevention of disorders modulated by PPARs, i.e., metabolic sy...

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Hauptverfasser:	KIM, SUNG SOO, LEE, JEONG-HYUNG, KIM, SEUNG JUN, YOO, SUNG-EUN, KIM, KWANG-ROK, CHEON, HYAE GYEONG, KIM, JONG HOON, MO, KIL WOONG, LEE, JAE MOK, PARK, SUNG DAE, KIM, NAM GEE, RHEE, SANG DAL, JUNG, WON HOON, KANG, HYE JUNG, YANG, SUNG-DON, KIM, SUN MEE, AHN, JIN HEE, KANG, SEUNG KYU, LEE, KOUN HO
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and thus, they are useful for the treatment and prevention of disorders modulated by PPARs, i.e., metabolic syndromes such as diabetes, obesity, arteriosclerosis, hyperlipidemia, hyperinsulinism and hypertension, inflammatory diseases such as osteoporosis, liver cirrhosis and asthma, and cancer.