COMPOSITIONS AS ADJUVANTS TO IMPROVE IMMUNE RESPONSES TO VACCINES AND METHODS OF USE

COMPOSITIONS AS ADJUVANTS TO IMPROVE IMMUNE RESPONSES TO VACCINES AND METHODS OF USE

The invention provides compositions containing an antigen and a TIM targetin g molecule. The invention additionally provides a TIM targeting molecule conjugate, for example, a TIM targeting molecule targeted to a therapeutic o r diagnostic moiety. The invention additionally provides methods of using...

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Hauptverfasser: SOO HOO, WILLIAM, JENSEN, ERIC R, THATTE, JAYANT, HELMICH, BRIAN K, MOLL, THOMAS, YEI, SOONPIN, CARLO, DENNIS J
Format: Patent
Sprache:eng ; fre
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CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator SOO HOO, WILLIAM
JENSEN, ERIC R
THATTE, JAYANT
HELMICH, BRIAN K
MOLL, THOMAS
YEI, SOONPIN
CARLO, DENNIS J
description The invention provides compositions containing an antigen and a TIM targetin g molecule. The invention additionally provides a TIM targeting molecule conjugate, for example, a TIM targeting molecule targeted to a therapeutic o r diagnostic moiety. The invention additionally provides methods of using such compositions. In one embodiment, the invention provides a method of stimulating an immune response in an individual by administering a compositi on comprising an antigen and a TIM targeting molecule in a pharmaceutically acceptable carrier. In another embodiment, the invention provides a method o f stimulating an immune response in an individual by administering an antigen and a TIM targeting molecule, which can be administered together in a single composition or separately.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title COMPOSITIONS AS ADJUVANTS TO IMPROVE IMMUNE RESPONSES TO VACCINES AND METHODS OF USE
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