PYRANONE COMPOUNDS USEFUL TO TREAT RETROVIRAL INFECTIONS

The present invention relates to compounds of formulae (I) and (II) (see formula I) (see formula II) which are pyran-2-ones, 5,6-dihydro-pyran-2-ones, 4-hydroxy-benzopyran-2-one s, 4- hydroxy-cycloalkyl[b]pyran-2-ones, and derivatives thereof, useful for inhibiting a retrovirus in a mammalian cell i...

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Hauptverfasser:	SKULNICK, HARVEY IRVING, LUKE, GEORGE P, MORRIS, JOEL, TURNER, STEVEN RONALD, THAISRIVONGS, SUVIT, GAMMILL, RONALD B, JOHNSON, PAUL D, SCHWARTZ, THERESA M, BUNDY, GORDON L, SKALETZKY, LOUIS L, TOMMASI, RUBEN A, STROHBACH, JOSEPH WALTER, ANDERSON, DAVID JOHN, ROMINES, KAREN RENE, ARISTOFF, PAUL ADRIAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to compounds of formulae (I) and (II) (see formula I) (see formula II) which are pyran-2-ones, 5,6-dihydro-pyran-2-ones, 4-hydroxy-benzopyran-2-one s, 4- hydroxy-cycloalkyl[b]pyran-2-ones, and derivatives thereof, useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus, wherein R10 an d R20 taken together are formulae (III) and (IV). (see formula III) (see formula IV)