ANTIBODY LINKED CATIONIC EMULSIONS AS DRUG DELIVERY SYSTEM

ANTIBODY LINKED CATIONIC EMULSIONS AS DRUG DELIVERY SYSTEM

A combination product comprising a positive oil in water emulsion wherein said emulsion comprises a compound presenting free NH2 groups, at its natural state, at the oil-water interface, and an antibody, wherein said compound is linked to said antibody by a heterobifunctional linker, linking said NH...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LAMBERT, GREGORY, GOLDSTEIN, DANNY KEREN-HAYESOD, NASSAR, TAHER, BENITA, SIMON, KADOUCHE, JEAN, RAZAFINDRATSITA, ALAIN, SADER, OLA
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:A combination product comprising a positive oil in water emulsion wherein said emulsion comprises a compound presenting free NH2 groups, at its natural state, at the oil-water interface, and an antibody, wherein said compound is linked to said antibody by a heterobifunctional linker, linking said NH2 groups to SH groups on the antibody hinge region.