PROCESS FOR CRYSTALLIZATION OF RAMIPRIL AND PREPARATION OF A HYDRATED FORM THEREOF

A process is provided for purification of optically impure Ramipril to obtain Ramipril(I) having optical purity of at least 99.9 %, wherein optically impure Ramipril is crystallized from an organic solvent selected from nitromethane, dimethoxymethane, diethoxymethane, and 2,2,-dimethoxy propane and...

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Hauptverfasser: DHAKE, VILAS NATHU, RANANAWARE, UMESH BABANRAO, SINGH, GIRIJ PAL
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:A process is provided for purification of optically impure Ramipril to obtain Ramipril(I) having optical purity of at least 99.9 %, wherein optically impure Ramipril is crystallized from an organic solvent selected from nitromethane, dimethoxymethane, diethoxymethane, and 2,2,-dimethoxy propane and mixtures thereof.