SUBSTITUTED AZOLE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE

The present invention provides azole derivatives of Formula (I), (see formula I) wherein the various variables are defined herein. The present invention also provides methods of their preparation, pharmaceutical compositions comprising the compounds of Formula (I), and their use in treating human or...

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Bibliographische Detailangaben
Hauptverfasser:	ANDREWS, ROBERT C, QUADA, JAMES C. JR, ARIMILLI, MURTY N, SUBRAMANIAN, GOVINDAN, MJALLI, ADNAN M.M, YARRAGUNTA, RAVINDRA R, XIE, RONGYUAN, POLISETTI, DHARMA R
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides azole derivatives of Formula (I), (see formula I) wherein the various variables are defined herein. The present invention also provides methods of their preparation, pharmaceutical compositions comprising the compounds of Formula (I), and their use in treating human or animal disorders. The compounds of the invention can be useful as inhibitors of protein tyrosine phosphatases and thus can be useful for the management, treatment, control, or the adjunct treatment of diseases mediated by PTPase activity. Such diseases include Type I diabetes and Type II diabetes.