METHOD OF DETECTING MUTATIONS ASSOCIATED WITH THROMBOSIS

The present invention provides a method for the simultaneous identification of two or more single base changes in a plurality of target nucleotide sequence s that are markers associated with cardiovascular diseases such as deep vein thrombosis and the like. Multiplex detection is accomplished using...

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Bibliographische Detailangaben
Hauptverfasser:	BLACK, MARGOT, KOBLER, DANIEL, BORTOLIN, SUSAN, JANECZKO, RICHARD A, FIELDHOUSE, DANIEL, MERANTE, FRANK, ZASTAWNY, ROMAN, MODI, HEMANSHU
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides a method for the simultaneous identification of two or more single base changes in a plurality of target nucleotide sequence s that are markers associated with cardiovascular diseases such as deep vein thrombosis and the like. Multiplex detection is accomplished using multiplex ed tagged allele specific primer extension (ASPE) and hybridization of such extended primers to a probe, preferably an addressable anti-tagged support.< /SDOAB>