OPERATOR INDEPENDENT PROGRAMMABLE SAMPLE PREPARATION AND ANALYSIS SYSTEM

The present invention provides a protocol and apparatus for enriching circulating tumor cells and other rare cells from blood, including debris an d other components, from samples with high precision and at high throughput rates. This invention discloses an improved processing system from previousl...

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Bibliographische Detailangaben
Hauptverfasser:	LAPEUS, DAVE, HARBART, THOMAS, HOWARD, DAVE, BENDELE, TERESA, KEENE, DOUGLAS, PAYNTER, DOUGLAS, RUTNER, HERMAN, KAGAN, MICHAEL, MAYES, JARED, PROHASKA, JERRY
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BASIC ELECTRIC ELEMENTS BEER BIOCHEMISTRY CALCULATING CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPUTING CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES COUNTING ELECTRIC SOLID STATE DEVICES NOT OTHERWISE PROVIDED FOR ELECTRICITY ENZYMOLOGY IMAGE DATA PROCESSING OR GENERATION, IN GENERAL INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SEMICONDUCTOR DEVICES SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides a protocol and apparatus for enriching circulating tumor cells and other rare cells from blood, including debris an d other components, from samples with high precision and at high throughput rates. This invention discloses an improved processing system from previousl y described semi-automated sample processing. The system further reduces operator intervention and hands-on time from prior systems. While this syste m has general utility in processing diverse materials, the system is configure d for sample processing of biological specimens to provide an enriched fractio n suitable for detection, enumeration and identification of target cells by appropriate analytical methodologies. The presence and quantities of such target cells in a sample specimen can utilized for screening and detection i n disease such as cancer, assessing early stage pre-metastatic cancer, monitoring for disease remission in response to therapy and selection of mor e effective dose regimens or alternative therapies in case of relapse.