PROCESS FOR THE PURIFICATION OF TERBINAFINE

Purification process for the preparation of the allylamine pharmaceutical terbinafine of formula (I), in free base form or acid addition salt form, by distilling crude terbinafine base, preferably by short path distillation, e.g. at a temperature above 100~C and reduced pressure, e.g. 0.2 mbar, and...

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Bibliographische Detailangaben
Hauptverfasser: PENN, GERHARD, BEUTLER, ULRICH
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Purification process for the preparation of the allylamine pharmaceutical terbinafine of formula (I), in free base form or acid addition salt form, by distilling crude terbinafine base, preferably by short path distillation, e.g. at a temperature above 100~C and reduced pressure, e.g. 0.2 mbar, and recovering the purified product in free base or acid addition salt form.