STABLE POLYMORPH OF BIFEPRUNOX MESILATE(7-(4-(1,1'-BIPHENYL)-3-YLMETHYL)-1-PIPERAZINYL)-2(3H)-BENZOXAZOLONE MONOMETHANESULFONATE

STABLE POLYMORPH OF BIFEPRUNOX MESILATE(7-(4-(1,1'-BIPHENYL)-3-YLMETHYL)-1-PIPERAZINYL)-2(3H)-BENZOXAZOLONE MONOMETHANESULFONATE

The invention relates to a stable polymorphic form of the compound 7-[4-([1,1'-biphenyl] -3-ylmethyl)-l -piperazinyl]­2(3H)-benzoxazolone monomethanesulfonate (INNM bifeprunox mesylate), a method for the preparation of said polymorphic form and its use in pharmaceutical products, especially in...

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Bibliographische Detailangaben
Hauptverfasser: KLEIN, GERRIT, HORST TER-AMSTEL VAN, MARIA J.L, EIJGENDAAL, IRENE, ZWIER, KLAAS
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention relates to a stable polymorphic form of the compound 7-[4-([1,1'-biphenyl] -3-ylmethyl)-l -piperazinyl]­2(3H)-benzoxazolone monomethanesulfonate (INNM bifeprunox mesylate), a method for the preparation of said polymorphic form and its use in pharmaceutical products, especially in pharmaceutical products for the treatment of psychotic disorders and Parkinson's disease.