REGULATION OF GUANINE NUCLEOTIDE EXCHANGE FACTOR

The invention relates generally to the methods of treating brain diseases an d compounds for treating brain diseases, and more specifically relates to usin g compounds that are able to modulate guanine nucleotide exchange factors for proteins belonging to the Rap family of small GTPases to treat dis...

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Bibliographische Detailangaben
Hauptverfasser:	GIBSON, LUCIEN, CHARLES, DONALD, MACKENZIE, SIMON, JOHN, MCFARLANE, MORAG, COOREMAN, ANN, KEWNEY, JUSTIN, PETER, BRESLIN, CATHERINE, MCPHEE, IAN, HAMMOND, STEPHEN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TESTING
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Beschreibung
Zusammenfassung:	The invention relates generally to the methods of treating brain diseases an d compounds for treating brain diseases, and more specifically relates to usin g compounds that are able to modulate guanine nucleotide exchange factors for proteins belonging to the Rap family of small GTPases to treat diseases of t he brain, such as Alzheimer's and Schizophrenia.