ANAPLASTIC LYMPHOMA KINASE MODULATORS AND METHODS OF USE

The present invention provides compounds and pharmaceutical compositions that are inhibitors of ALK. The invention also comprises use of such compounds and compositions to treat diseases mediated by ALK, including diseases such as cancer, immunological disorders, cardiovascular diseases, and other d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	MANALO, JEAN-CLAIRE L, BUSSENIUS, JOERG, KENNEDY, ABIGAIL R, PETO, CSABA J, DUBENKO, LARISA, KHOURY, RICHARD G, CURTIS, JEFFRY KIMO, BLAZEY, CHARLES M, COSTANZO, SIMONA, KIM, ANGIE I, BOWLES, OWEN JOSEPH, ANAND, NEEL KUMAR, RICE, KENNETH D, TSANG, TSZE H
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides compounds and pharmaceutical compositions that are inhibitors of ALK. The invention also comprises use of such compounds and compositions to treat diseases mediated by ALK, including diseases such as cancer, immunological disorders, cardiovascular diseases, and other degenerative disorders. Compounds of this invention fall within the following general formula. (see formula I)