REDUCING PROTEIN A LEACHING DURING PROTEIN A AFFINITY CHROMATOGRAPHY
A method for reducing leaching of protein A during protein A affinity chromatography is described which involves reducing temperature or pH of, or by adding one or more protease inhibitors to, a composition that is subjected to protein A affinity chromatography. L'invention concerne un procédé...
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| Format: | Patent |
| Sprache: | eng ; fre |
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| Zusammenfassung: | A method for reducing leaching of protein A during protein A affinity chromatography is described which involves reducing temperature or pH of, or by adding one or more protease inhibitors to, a composition that is subjected to protein A affinity chromatography.
L'invention concerne un procédé permettant de réduire la lixiviation de la protéine A lors de la chromatographie d'affinité sur la protéine A, qui consiste à réduire la température ou le pH d'une composition soumise à une chromatographie d'affinité sur la protéine A, ou d'ajouter à ladite composition au moins un inhibiteur de protéase. |
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