FUNCTIONALLY RECONSTITUTED VIRAL MEMBRANES CONTAINING ADJUVANT

The present invention relates to vaccines directed against antigens such as membrane proteins from pathogens or tumor cells. The invention further relat es to methods of forming reconstituted viral membranes, with membrane fusion activity, which are lipid bilayer membranes preferably containing natu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	STEGMANN, ANTONIUS JOHANNES HENDRIKUS, WILSCHUT, JAN CHRISTIAAN, VAN BERKUM, JOHANNES HENRICUS GERARDUS
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to vaccines directed against antigens such as membrane proteins from pathogens or tumor cells. The invention further relat es to methods of forming reconstituted viral membranes, with membrane fusion activity, which are lipid bilayer membranes preferably containing natural lipids of a virus, a viral fusion protein, one or more optional further antigens as well as amphiphilic adjuvants. Pharmaceutical compositions comprising such reconstituted viral membranes are also part of the invention .