GUANIDINO-SUBSTITUTED QUINAZOLINONE COMPOUNDS AS MC4-R AGONISTS

A variety of small molecule, guanidine-containing molecules capable of actin g as MC4-R agonists are provided. The compounds are useful in treating MC4-R mediated diseases when administered to subjects. The compounds have the structure IA, IB, and IC where the values of the variables are defined her...

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Hauptverfasser:	AURRECOECHEA, NATALIA, BARVIAN, KEVIN K, CHU, DANIEL, CHAUDER, BRIAN A, SPEAKE, JASON D, MUSSO, DAVID L, BOYCE, RUSTUM S, DE ARMAS KUNTZ, JUDITH, THOMPSON, BRIAN D, CONLEE, CHRISTOPHER R, SMITH, AARON, THOMSON, STEPHEN A, DU, KIEN S, SWAIN, WILLIAM R, BISHOP, MICHAEL J
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	A variety of small molecule, guanidine-containing molecules capable of actin g as MC4-R agonists are provided. The compounds are useful in treating MC4-R mediated diseases when administered to subjects. The compounds have the structure IA, IB, and IC where the values of the variables are defined herei n.