COMBINATION THERAPIES FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

The invention features a method of treating asthma, COPD, allergic rhinitis, and infectious rhinitis by administering a first pharmaceutical agent including one or more compounds selected from the quarternary ammonium compounds of formulae I~ V and a second pharmaceutical agent including one o r more pharmaceutical agents selected from Adenosine A2a Receptor Agonists, D2 - Dopamine Receptor Agonists, Phosphodiesterase Inhibitors (PDE's), corticosteroids, norepinephrine reuptake inhibitors, 4-hydroxy-7-[2-[2-[3- [ 2- phenylethoxy]- propylsulphonyllethylamino] ethyl] -1,3-benzothiazol-2(3H)-on e, and pharmaceutically acceptable salts thereof, and non-quarternized antimuscarinic compounds.