PROCESSES FOR THE PREPARATION OF N-((((PYRIDINYLOXY)-PHENYLAMINO) QUINAZOLINYL)-ALLYL) ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS WELL AS INTERMEDIATES OF SUCH PROCESSES AND PROCESSES FOR THE PREPARATION OF SUCH INTERMEDIATES

The invention relates to processes for preparing compounds of the formula (1 ) and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R1, R3, R4, R6 R11, R13 R14 R15, R16, R17, k, I, and m are as define d herein. The present invention also relates to intermediates represent...

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Hauptverfasser: RIPIN, DAVID HAROLD BROWN, VETELINO, MICHAEL GIRARD, WEI, LULIN
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creator RIPIN, DAVID HAROLD BROWN
VETELINO, MICHAEL GIRARD
WEI, LULIN
description The invention relates to processes for preparing compounds of the formula (1 ) and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R1, R3, R4, R6 R11, R13 R14 R15, R16, R17, k, I, and m are as define d herein. The present invention also relates to intermediates represented by t he formula (3a) wherin R4, and R5 are independently selected from hydrogen and C1- C6alkyl; each R13, R14, R15 and R16 is independently selected from hydrogen, C1-C6alkyl and CH2OH, R17 and R18 are independently C1-C6 alkyl, and k and I are independently an integer from 1 to 3, as well as to a process for preparing these intermediates.
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The present invention also relates to intermediates represented by t he formula (3a) wherin R4, and R5 are independently selected from hydrogen and C1- C6alkyl; each R13, R14, R15 and R16 is independently selected from hydrogen, C1-C6alkyl and CH2OH, R17 and R18 are independently C1-C6 alkyl, and k and I are independently an integer from 1 to 3, as well as to a process for preparing these intermediates.</description><edition>7</edition><language>eng ; fre</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20041021&amp;DB=EPODOC&amp;CC=CA&amp;NR=2521348A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20041021&amp;DB=EPODOC&amp;CC=CA&amp;NR=2521348A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RIPIN, DAVID HAROLD BROWN</creatorcontrib><creatorcontrib>VETELINO, MICHAEL GIRARD</creatorcontrib><creatorcontrib>WEI, LULIN</creatorcontrib><title>PROCESSES FOR THE PREPARATION OF N-((((PYRIDINYLOXY)-PHENYLAMINO) QUINAZOLINYL)-ALLYL) ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS WELL AS INTERMEDIATES OF SUCH PROCESSES AND PROCESSES FOR THE PREPARATION OF SUCH INTERMEDIATES</title><description>The invention relates to processes for preparing compounds of the formula (1 ) and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R1, R3, R4, R6 R11, R13 R14 R15, R16, R17, k, I, and m are as define d herein. 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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title PROCESSES FOR THE PREPARATION OF N-((((PYRIDINYLOXY)-PHENYLAMINO) QUINAZOLINYL)-ALLYL) ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS WELL AS INTERMEDIATES OF SUCH PROCESSES AND PROCESSES FOR THE PREPARATION OF SUCH INTERMEDIATES
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