BENZOPYRAN COMPOUNDS USEFUL FOR TREATING INFLAMMATORY CONDITIONS

The subject invention concerns methods and compounds that have utility in th e treatment of a condition associated with cyclooxygenase-2 mediated disorders . Compounds of particular interest are benzopyrans and their analogs defined b y formula (1). Wherein Z, X, R1, R2, R3, and R4 are as described...

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Hauptverfasser: ASTON, KARL WILLIAM, YU, YI, SPRINGER, JOHN ROBERT, KOSZYK, FRANCIS, TALLEY, JOHN J, HAMPER, BRUCE CAMERON, WANG, LIJUAN JANE, MCCALL, JOHN MICHAEL, XING, LI, LIAO, SUBO, HALLINAN, E. ANN, DEPROW, ANGELA, BROWN, DAVID LOUIS, LUDWIG, CINDY, LIMBURG, DAVID CHRISTOPHER, FLETCHER, THERESA, HUFF, RENEE, KRAMER, STEVEN, CARTER, JEFFERY STEVEN, KIEFER, JAMES RICHARD JR
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The subject invention concerns methods and compounds that have utility in th e treatment of a condition associated with cyclooxygenase-2 mediated disorders . Compounds of particular interest are benzopyrans and their analogs defined b y formula (1). Wherein Z, X, R1, R2, R3, and R4 are as described in specification.