HETEROCYCLIC COMPOUNDS AND METHODS OF USE

The invention relates to compounds of the formulae (I) to (III) wherein the substituents are as defined in the specification. These compounds have kinas e inhibitory activity, such as VEGFR/KDR inhibitory activity. Accordingly, the compounds of the formulae (I) to (III) would be useful in the preven...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	PATEL, VINOD F, ELBAUM, DANIEL, ASKEW, BENNY C., JR, VAN DER PLAS, SIMON, DI PIETRO, LUCIAN V, GERMAIN, JULIE, KIM, JOSEPH L, POTASHMAN, MICHELE, HARMANGE, JEANRISTOPHE, HABGOOD, GREGORY J
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to compounds of the formulae (I) to (III) wherein the substituents are as defined in the specification. These compounds have kinas e inhibitory activity, such as VEGFR/KDR inhibitory activity. Accordingly, the compounds of the formulae (I) to (III) would be useful in the prevention and treatment of angiogenesis related disorders, ophthalmological conditions, proliferative diseases, inflammatory diseases, and other pathological conditions as described in the specification.