NEW ARYLPIPERAZINYL COMPOUNDS

The invention relates to 5-HT receptor agonists or antagonists. Novel arylpiperazinyl sulfonamide compounds represented by formula (I), and synthesis and uses thereof for treating diseases including those mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include centr...

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Bibliographische Detailangaben
Hauptverfasser:	SHARADENDU, ANURAG, SHA, SHARON, CHERUKU, SRINIVASA RAO, NUDELMAN, RAPHAEL, BAR-HAIM, SHAY, MOHANTY, PRADYUMNA, MARANTZ, YAEL, NOIMAN, SILVIA, CHEN, DONGLI, DHANOA, DALE S, BECKER, OREN, HEIFETZ, ALEXANDER, INBAL, BOAZ, FICHMAN, MERAV
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to 5-HT receptor agonists or antagonists. Novel arylpiperazinyl sulfonamide compounds represented by formula (I), and synthesis and uses thereof for treating diseases including those mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include central nervous system disorders such as generalized anxiety disorder, ADD/ADHD, neural injury, stroke, and migraine. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.