PYRAZOLE COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES

The present invention relates to pharmaceutical compositions comprising compounds of the Formula (I), and methods of selectively inhibiting or antagonizing the .alpha.V.beta.3 and/or the .alpha. V.beta.5 integrin withou t significantly inhibiting the .alpha. V.beta.6 integrin.

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Bibliographische Detailangaben
Hauptverfasser:	WANG, YAPING, DOWNS, VICTORIA, RUSSELL, MARK, CHEN, BARBARA B, SPANGLER, DALE P, KHILEVICH, ALBERT, PENNING, THOMAS D, GANDHI, PREETE, BOYS, MARK L, HUFF, RENEE M
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to pharmaceutical compositions comprising compounds of the Formula (I), and methods of selectively inhibiting or antagonizing the .alpha.V.beta.3 and/or the .alpha. V.beta.5 integrin withou t significantly inhibiting the .alpha. V.beta.6 integrin.