GENETICALLY ENGINEERED TOXOPLASMA GONDII P30 ANTIGEN, IMPROVED ANTIGEN COCKTAIL AND USES THEREOF

The present invention relates to a genetically engineered P30 antigen and a combination or mixture of antigens (e.g., the genetically engineered P30 antigen and P35) that may be used in the detection of IgM and/or IgG antibodies to Toxoplasma gondii. Furthermore, the present invention also relates t...

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Hauptverfasser:	BLIESE, TIMOTHY R, PATEL, CHANDU B, GINSBURG, SANFORD R, MAINE, GREGORY T
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a genetically engineered P30 antigen and a combination or mixture of antigens (e.g., the genetically engineered P30 antigen and P35) that may be used in the detection of IgM and/or IgG antibodies to Toxoplasma gondii. Furthermore, the present invention also relates to methods of using this genetically engineered P30 antigen and combination of antigens, antibodies raised against this genetically engineered P30 antigen and combination of antigens, as well as kits and vaccines containing the genetically engineered P30 antigen and antigens present in the combination. L'invention concerne un antigène P30 génétiquement modifié et une combinaison ou un mélange d'antigènes (par ex., l'antigène P30 génétiquement modifié et P35) pouvant servir à la détection d'anticorps IgM et/ou IgG au Toxoplasma gondii. La présente invention porte également sur des procédés pour utiliser cet antigène P30 génétiquement modifié et des combinaisons d'antigènes, des anticorps contre cet antigène P30 génétiquement modifié et ces combinaisons d'antigènes, ainsi que sur des kits et des vaccins contenant ledit antigène P30 génétiquement modifié et des antigènes présents dans ladite combinaison.