CRYSTALLIZATION METHOD AND APPARATUS USING AN IMPINGING PLATE ASSEMBLY

CRYSTALLIZATION METHOD AND APPARATUS USING AN IMPINGING PLATE ASSEMBLY

A crystallization process for generating a pharmaceutical product from solutions of pharmaceutically active compounds or their reactive intermediat es employs fluid jet streams containing pharmaceutically active ingredients, appropriate anti-solvents and/or their reactive intermediates capable of pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: AM ENDE, DAVID JON, BRENEK, STEVEN JAMES
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SEPARATION
TRANSPORTING
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Beschreibung
Zusammenfassung:A crystallization process for generating a pharmaceutical product from solutions of pharmaceutically active compounds or their reactive intermediat es employs fluid jet streams containing pharmaceutically active ingredients, appropriate anti-solvents and/or their reactive intermediates capable of producing a pharmaceutical product with desired particle size characteristic s upon mixing, chemical reaction, nucleation and precipitation. The jet stream s are directed towards and impinging plate, and mixing occurs as the jet strea ms impinge the plate at a desired area of impact.