PROCESS FOR PRODUCING PAROXETINE HYDROCHLORIDE HYDRATE

A process for producing paroxetine hydrochloride hydrate, which comprises reacting (3S,4R)-1-tert-butoxycarbonyl-4-(4-fluorophenyl)-3-[(3,4- methylenedioxy)phenoxymethyl]piperidine with hydrogen chloride in the presen ce of water and then precipitating crystals in the presence of water.

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Bibliographische Detailangaben
Hauptverfasser: YAMAZAKI, SHIGEYA, YOSHIKAWA, TAICHI
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:A process for producing paroxetine hydrochloride hydrate, which comprises reacting (3S,4R)-1-tert-butoxycarbonyl-4-(4-fluorophenyl)-3-[(3,4- methylenedioxy)phenoxymethyl]piperidine with hydrogen chloride in the presen ce of water and then precipitating crystals in the presence of water.