METHOD AND APPARATUS FOR FAIMS WITH A LASER-BASED IONIZATIONSOURCE

A method of separating ions comprises applying a spot of a sample material t o a target plate. The target plate is mounted in fluid communication with an ion inlet orifice of a FAIMS analyzer region and externally to the FAIMS analyzer region. Using a laser light source that is disposed external to...

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Hauptverfasser: DWORSCHAK, RAGNAR, HILTON, CHRISTOPHER KARL, BELFORD, MICHAEL WILLIAM, YOST, RICHARD A, GUEVREMONT, ROGER
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creator DWORSCHAK, RAGNAR
HILTON, CHRISTOPHER KARL
BELFORD, MICHAEL WILLIAM
YOST, RICHARD A
GUEVREMONT, ROGER
description A method of separating ions comprises applying a spot of a sample material t o a target plate. The target plate is mounted in fluid communication with an ion inlet orifice of a FAIMS analyzer region and externally to the FAIMS analyzer region. Using a laser light source that is disposed external to the FAIMS analyzer region, the target plate is irradiat ed with light of a predetermined wavelength, the light of a predetermined wavelength being selected to affect the sample material applied to the target plate so as to produce ions of the sample material. The ions of the sample material are directed along an ion flow path between the targe t plate and FAIMS analyzer region, via the ion inlet orifice. A flow of a gas is directed counter-current to the ion flow path and passing through the target plate. The flow of gas through the target plate assists in desolvation of ions and directs neutral molecules away from the FAIMS analyz er region.
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language eng ; fre
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subjects BASIC ELECTRIC ELEMENTS
ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
ELECTRICITY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PHYSICS
SEPARATION
TESTING
TRANSPORTING
title METHOD AND APPARATUS FOR FAIMS WITH A LASER-BASED IONIZATIONSOURCE
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