METHOD AND APPARATUS FOR FAIMS WITH A LASER-BASED IONIZATIONSOURCE

A method of separating ions comprises applying a spot of a sample material t o a target plate. The target plate is mounted in fluid communication with an ion inlet orifice of a FAIMS analyzer region and externally to the FAIMS analyzer region. Using a laser light source that is disposed external to...

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Bibliographische Detailangaben
Hauptverfasser:	DWORSCHAK, RAGNAR, HILTON, CHRISTOPHER KARL, BELFORD, MICHAEL WILLIAM, YOST, RICHARD A, GUEVREMONT, ROGER
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BASIC ELECTRIC ELEMENTS ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS ELECTRICITY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS SEPARATION TESTING TRANSPORTING
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Beschreibung
Zusammenfassung:	A method of separating ions comprises applying a spot of a sample material t o a target plate. The target plate is mounted in fluid communication with an ion inlet orifice of a FAIMS analyzer region and externally to the FAIMS analyzer region. Using a laser light source that is disposed external to the FAIMS analyzer region, the target plate is irradiat ed with light of a predetermined wavelength, the light of a predetermined wavelength being selected to affect the sample material applied to the target plate so as to produce ions of the sample material. The ions of the sample material are directed along an ion flow path between the targe t plate and FAIMS analyzer region, via the ion inlet orifice. A flow of a gas is directed counter-current to the ion flow path and passing through the target plate. The flow of gas through the target plate assists in desolvation of ions and directs neutral molecules away from the FAIMS analyz er region.