NON-POLYMERIC HEMATOPOIETIC CELL CLOTS FOR DELIVERY OF ACTIVE AGENTS

The invention encompasses a method of and apparatus for delivering a substance. The delivery of a substance entails administering to a subject a non polymeric hematopoeitic cell clot having a substance incorporated therein. The non polymeric hematopoeitic cell clot functions as the delivery vehicle...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	EVANS, CHRISTOPHER, PASCHER, ARNULF, GHIVIZZANI, STEVEN, PALMER, GLYN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention encompasses a method of and apparatus for delivering a substance. The delivery of a substance entails administering to a subject a non polymeric hematopoeitic cell clot having a substance incorporated therein. The non polymeric hematopoeitic cell clot functions as the delivery vehicle for the substance. Specifically, the invention relates to a substance delivery system comprising: a bone marrow cell clot having a substance incorporated therein, wherein the substance comprises a gene delivery vehicle, proteins, bioactive molecules, or genetically engineered cells and wherein a polymer matrix is not incorporated into the clot or used as the structure for the clot having a substance incorporated therein. The invention also relates to methods and uses thereof for delivering a substance to a subject.