PROCESS FOR THE PREPARATION OF 4-METHYL-THIAZOLE-5-CARBALDEHYDE INTERMEDIATE

The present invention provides a process for the preparation of 4-methyl-5- formyl-thiazole of the formula (I), which comprises reducing the thiazole ester of the formula (III) to thiazole alcohol of the formula (IV), using a sodium borohydride in the presence of AlCl3 in a solvent and oxidising the...

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Hauptverfasser: LUTHRA, PARVEN KUMAR, KAMMA, RAMAKRISHNA, VYAS, RAJESH, DESHPANDE, PANDURANG BALWANT
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creator LUTHRA, PARVEN KUMAR
KAMMA, RAMAKRISHNA
VYAS, RAJESH
DESHPANDE, PANDURANG BALWANT
description The present invention provides a process for the preparation of 4-methyl-5- formyl-thiazole of the formula (I), which comprises reducing the thiazole ester of the formula (III) to thiazole alcohol of the formula (IV), using a sodium borohydride in the presence of AlCl3 in a solvent and oxidising the thiazole alcohol of the formula (IV) to obtain 4-methyl-5-formyl-thiazole of the formula (I) using an oxidizing agent.
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subjects APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title PROCESS FOR THE PREPARATION OF 4-METHYL-THIAZOLE-5-CARBALDEHYDE INTERMEDIATE
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