PROCESS FOR THE PREPARATION OF 4-METHYL-THIAZOLE-5-CARBALDEHYDE INTERMEDIATE

PROCESS FOR THE PREPARATION OF 4-METHYL-THIAZOLE-5-CARBALDEHYDE INTERMEDIATE

The present invention provides a process for the preparation of 4-methyl-5- formyl-thiazole of the formula (I), which comprises reducing the thiazole ester of the formula (III) to thiazole alcohol of the formula (IV), using a sodium borohydride in the presence of AlCl3 in a solvent and oxidising the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LUTHRA, PARVEN KUMAR, KAMMA, RAMAKRISHNA, VYAS, RAJESH, DESHPANDE, PANDURANG BALWANT
Format: Patent
Sprache:eng ; fre
Schlagworte:
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention provides a process for the preparation of 4-methyl-5- formyl-thiazole of the formula (I), which comprises reducing the thiazole ester of the formula (III) to thiazole alcohol of the formula (IV), using a sodium borohydride in the presence of AlCl3 in a solvent and oxidising the thiazole alcohol of the formula (IV) to obtain 4-methyl-5-formyl-thiazole of the formula (I) using an oxidizing agent.