SUBSTITUTED TETRACYCLINE COMPOUNDS

The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infectio ns and neoplasms, as well as other known applications for minocycline and tetr...

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Hauptverfasser: ASSEFA, HAREGEWEIN, SHEAHAN, PAUL, VISKI, PETER, BERNIAC, JOEL, NIHLAWI, MOHAMMED, ISMAIL, MOHAMED Y, FRECHETTE, ROGER, WARCHOL, TADEUSZ, KIM, OAK A, MECHICHE, RACHID, OHEMENG, KWASI, VERMA, ATUL K, BHATIA, BEENA, ABATO, PAUL, TOURIGNY, JUSTIN, REDDY, LAXMA, CHEN, JACKSON, SIZENSKY, EMMANUELLE, AMOO, VICTOR, BANDARAGE, UPUL, PEARSON, ANDRE, NELSON, MARK L, MCINTYRE, LAURA, MATHEWS, JUDE
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infectio ns and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.