DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS

Benzimidazole derivatives of formula (I) , which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includ es methods of making such benzimidazole derivatives as well as methods of using the same in the treatment of hyperproliferative diseases. (I)

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Bibliographische Detailangaben
Hauptverfasser:	JOHNSON, NEIL W, SEMONES, MARCUS, SAMMOND, DOUGLAS MCCORD, CHEUNG, MUI, EMERSON, HOLLY KATHLEEN, NAILOR, KRISTEN ELIZABETH, CHAMBERLAIN, STANLEY DAWES
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Benzimidazole derivatives of formula (I) , which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includ es methods of making such benzimidazole derivatives as well as methods of using the same in the treatment of hyperproliferative diseases. (I)