DRUG DELIVERY SYSTEM FOR SUBCONJUNCTIVAL ADMINISTRATION OF FINE PARTICLES

The present invention provides an excellent drug delivery system to posterior segments. An injection according to the present invention is a subconjunctival injection which comprises fine particles containing a drug and enables the drug to deliver to the posterior segments. The drug can be efficient...

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Bibliographische Detailangaben
Hauptverfasser: YAMADA, KAZUHITO, KUWANO, MITSUAKI
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:The present invention provides an excellent drug delivery system to posterior segments. An injection according to the present invention is a subconjunctival injection which comprises fine particles containing a drug and enables the drug to deliver to the posterior segments. The drug can be efficiently delivered to the posterior segments (such as a retina, a choroid and an optic nerve) while scarcely injuring ophthalmic tissues by administering the fine particles containing the drug subconjunctivally Preferred fine particles are made of a synthetic biodegradable polymer, their average particle dispersed in the fine particles uniformly. Preferred diameter is 50 nm to 150 µ m, and the drug is drugs are anti-inflammatories, immunosuppressors, antivirals, anticancer drugs, angiogenesis inhibitors, optic neural protectants, antimicrovials and antifungal .agents.