NICOTINAMIDE DERIVATIVES USEFUL AS PDE4 INHIBITORS
The invention relates to nicotinamide derivatives of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The nicotinamide derivatives according to the present invention are phosphodiesterase-4 inhib...
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| creator | MARFAT, ANTHONY MAGEE, THOMAS VICTOR MATHIAS, JOHN PAUL HENDERSON, ALAN JOHN GAUTIER, ELISABETH COLETTE LOUISE MONAGHAN, SANDRA MARINA STAMMEN, BLANDA LUZIA CHRISTA BAILEY, SIMON MCLEOD, DALE GORDON |
| description | The invention relates to nicotinamide derivatives of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The nicotinamide derivatives according to the present invention are phosphodiesterase-4 inhibitors and are useful in numerous diseases, disorders and ( conditions, in particular inflammatory, allergic, respiratory diseases, disorders and conditions, as well as wounds. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NICOTINAMIDE DERIVATIVES USEFUL AS PDE4 INHIBITORS |
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