NICOTINAMIDE DERIVATIVES USEFUL AS PDE4 INHIBITORS

The invention relates to nicotinamide derivatives of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The nicotinamide derivatives according to the present invention are phosphodiesterase-4 inhib...

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Bibliographische Detailangaben
Hauptverfasser:	MARFAT, ANTHONY, MAGEE, THOMAS VICTOR, MATHIAS, JOHN PAUL, HENDERSON, ALAN JOHN, GAUTIER, ELISABETH COLETTE LOUISE, MONAGHAN, SANDRA MARINA, STAMMEN, BLANDA LUZIA CHRISTA, BAILEY, SIMON, MCLEOD, DALE GORDON
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to nicotinamide derivatives of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The nicotinamide derivatives according to the present invention are phosphodiesterase-4 inhibitors and are useful in numerous diseases, disorders and ( conditions, in particular inflammatory, allergic, respiratory diseases, disorders and conditions, as well as wounds.