NICOTINAMIDE DERIVATES USEFUL AS P38 INHIBITORS

Compounds of formula (I), are inhibitors of p38 kinase and are useful in the treatment of conditions or disease states mediated by p38 kinase activity or mediated by cytokines produced by the activity of p38. L'invention concerne des composés de la formule (I), qui sont des inhibiteurs de la ki...

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Hauptverfasser:	WALKER, ANN LOUISE, ASTON, NICOLA MARY, BAMBOROUGH, PAUL
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Compounds of formula (I), are inhibitors of p38 kinase and are useful in the treatment of conditions or disease states mediated by p38 kinase activity or mediated by cytokines produced by the activity of p38. L'invention concerne des composés de la formule (I), qui sont des inhibiteurs de la kinase p38 utiles dans le traitement de pathologies ou de maladies induites par l'action de la kinase p38 ou par des cytokines produites par l'action de la kinase p38.