NOVEL PROTEINS AND NUCLEIC ACIDS ENCODING SAME

The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide...

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Hauptverfasser:	GERLACH, VALERIE L, BERGHS, CONSTANCE, CASMAN, STACIE J, ZHONG, MEI, ELLERMAN, KAREN, PENA, CAROL E. A, RASTELLI, LUCA, FURTAK, KATARZYNA, MACDOUGALL, JOHN R, SMITHSON, GLENNDA, LIU, XIAOHONG, JI, WEIZHEN, GUO, XIAOJIA, EDINGER, SHLOMIT R, MILLET, ISABELLE, SHIMKETS, RICHARD A, SHENOY, SURESH G, LI, LI, ANDERSON, DAVID W, GANGOLLI, ESHA A, GUNTHER, ERIK, STONE, DAVID J, SPYTEK, KIMBERLY A, MISHRA, VISHNU S, TAUPIER, RAYMOND J., JR, BAUMGARTNER, JASON C, TCHERNEV, VELIZAR T, GILBERT, JENNIFER A, ZERHUSEN, BRYAN D, WOLENC, ADAM R, CHANT, JOHN S, VERNET, CORINE A. M, SPADERNA, STEVEN K, PATTURAJAN, MEERA, BURGESS, CATHERINE E, ORT, TATIANA, GORMAN, LINDA, MILLER, CHARLES E, PADIGARU, MURALIDHARA, BALLINGER, ROBERT A
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.