COMPOSITIONS AND METHODS FOR INHIBITING ECCRINE PERSPIRATIONIN HUMANS

COMPOSITIONS AND METHODS FOR INHIBITING ECCRINE PERSPIRATIONIN HUMANS

Non-pathological, physiologically normal sweating is inhibited through use o f an a muscarinic anticholinergic amine that blocks parasympathetic stimuli fr om cholinergic nerve fibers to an innerved sweat gland. The anticholinergic age nt is included in a form adapted to be topically applied to comm...

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Bibliographische Detailangaben
1. Verfasser: LUKACSKO, ALISON B
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
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Zusammenfassung:Non-pathological, physiologically normal sweating is inhibited through use o f an a muscarinic anticholinergic amine that blocks parasympathetic stimuli fr om cholinergic nerve fibers to an innerved sweat gland. The anticholinergic age nt is included in a form adapted to be topically applied to commonly sweaty are as of the body. Side effects are minimized by employing amines which are charge d at physiological pH, thereby minimizing their ability to cross biological membranes. The most prefered anticholinergic agents are salts of quaternary amines (quaternary ammonium salts) which are always charged.