VACCINE FORMULATION POTENTIATED BY THE COMBINATION OF A DNA AND AN ANTIGEN

Formulation of vaccine antigens, containing as main components: a-) one or several DNA expressing one or several proteins in the immunized individuals and b-) a viral antigen, in appropriate proportions. The novelty of the invention is given by the enhancing effect of at least one component on the i...

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Hauptverfasser: MORALES GRILLO, JUAN, MARTINEZ DONATO, GILLIAN, DUENAS CARRERA, SANTIAGO, MUSACCHIO LASA, ALEXIS, ALVAREZ-LAJONCHERE PONCE DE LEON, LIZ, ALVAREZ OBREGON, JULIO C, PAJON FEYT, ROLANDO, VINA RODRIGUEZ, ARIEL, ACOSTA RIVERO, NELSON
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Formulation of vaccine antigens, containing as main components: a-) one or several DNA expressing one or several proteins in the immunized individuals and b-) a viral antigen, in appropriate proportions. The novelty of the invention is given by the enhancing effect of at least one component on the immune response generated against the other one. Development of new formulations, minimizing the number of components that enhance and diversify the spectrum of immune response against different pathogenic entities and generating combined vaccines against pathogens. These formulations can be applied in the pharmaceutical industry for preventive and-or therapeutic use in human.