VACCINE FORMULATION POTENTIATED BY THE COMBINATION OF A DNA AND AN ANTIGEN

The invention relates to a vaccine antigen formulation containing the following main components: a) one or more DNAs that express one or more proteins in the immunised individual and b) a viral antigen, in suitable proportions. The novelty of the invention lies in the potentiating effect exerted by...

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Bibliographische Detailangaben
Hauptverfasser:	MORALES GRILLO, JUAN, MARTINEZ DONATO, GILLIAN, DUENAS CARRERA, SANTIAGO, MUSACCHIO LASA, ALEXIS, ALVAREZ OBREGON, JULIO C, ALVAREZ-LAJONCHERE PONCE DE LEON, LIZ, PAJON FEYT, ROLANDO, VINA RODRIGUEZ, ARIEL, ACOSTA RIVERO, NELSON
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to a vaccine antigen formulation containing the following main components: a) one or more DNAs that express one or more proteins in the immunised individual and b) a viral antigen, in suitable proportions. The novelty of the invention lies in the potentiating effect exerted by at least one of the components on the immune response generated against the other. The invention also relates to the development of novel formulations that minimise the number of components that can amplify and potentiate the range of immune response against different pathogenic entitie s and generate combined vaccines against pathogenic entities. Said formulation s are suitable for use in the pharmaceutical industry for prophylactic and/or therapeutic purposes in individuals.