NON-PEPTIDE GNRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USE, AND PROCESSES FOR PREPARING THEM

NON-PEPTIDE GNRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USE, AND PROCESSES FOR PREPARING THEM

Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin- releasing hormone are described. Such compounds and their pharmaceutically acceptable salts, prodrugs, and active metabolites are suitable for treating mammalian reproductive disorders and steroid hormone-dependent tumors as w...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: CHRISTIE, LANCE CHRISTOPHER, PADERES, GENEVIEVE D, DO, QUYEN-QUYEN THUY, RAJAPAKSE, RANJAN JAGATH, TOMPKINS, EILEEN VALENZUELA, FENG, JUN, ANDERES, KENNA LYNN, PATHAK, VED P, HONG, YUFENG, VAZIR, HARESH, SHACKELFORD, SCOTT, IATSIMIRSKAIA, EUGENIA ANATOLIEVNA, LUTHIN, DAVID ROBERT, ANDERSON, MARK B, LI, HAITAO, GOETZEN, THOMAS, SUN, ERIC T, TRUESDALE, LARRY KENNETH
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin- releasing hormone are described. Such compounds and their pharmaceutically acceptable salts, prodrugs, and active metabolites are suitable for treating mammalian reproductive disorders and steroid hormone-dependent tumors as wel l as for regulating fertility, where suppression of gonadotropin release is indicated. Methods for synthesizing the compounds and intermediates useful i n their preparation are also described.