PROCESS FOR THE PREPARATION OF 4-AMINO-1-HYDROXYBUTYLIDENE-1, 1-BIPHOSPHONIC ACID

This invention is related with the preparation of 4-amino-1-hydroxybutyliden e- 1, 1-biphosphonic acid or salts thereof. The reaction of 4-aminobutyric acid wi th phosphorous acid and phosphorus trichloride in the presence of aralkyl or alkyl ethoxylates or triglycerides or plant or animal oils or t...

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Bibliographische Detailangaben
Hauptverfasser: ASLAN, TUNCER, OZARSLAN, A. EVREN, SAHBAZ, FILIZ, DABAK, KADIR
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:This invention is related with the preparation of 4-amino-1-hydroxybutyliden e- 1, 1-biphosphonic acid or salts thereof. The reaction of 4-aminobutyric acid wi th phosphorous acid and phosphorus trichloride in the presence of aralkyl or alkyl ethoxylates or triglycerides or plant or animal oils or their derivatives; and recovering o f 4-amino-1- hydroxybutylidene-1,1-biphosphonic acid or salts thereof are described. The main feature of the invention is in the use of the above-defined non-ionic emulsifying agents in the phosphonylation reaction.