PROCESS FOR THE PREPARATION OF 4-AMINO-1-HYDROXYBUTYLIDENE-1, 1-BIPHOSPHONIC ACID
This invention is related with the preparation of 4-amino-1-hydroxybutyliden e- 1, 1-biphosphonic acid or salts thereof. The reaction of 4-aminobutyric acid wi th phosphorous acid and phosphorus trichloride in the presence of aralkyl or alkyl ethoxylates or triglycerides or plant or animal oils or t...
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Zusammenfassung: | This invention is related with the preparation of 4-amino-1-hydroxybutyliden e- 1, 1-biphosphonic acid or salts thereof. The reaction of 4-aminobutyric acid wi th phosphorous acid and phosphorus trichloride in the presence of aralkyl or alkyl ethoxylates or triglycerides or plant or animal oils or their derivatives; and recovering o f 4-amino-1- hydroxybutylidene-1,1-biphosphonic acid or salts thereof are described. The main feature of the invention is in the use of the above-defined non-ionic emulsifying agents in the phosphonylation reaction. |
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