IL-28 POLYPEPTIDES AND POLYNUCLEOTIDS

The present invention relates to polynucleotide and polypeptide molecules for zcyto20, zcyto21, zcyto22, zcyto24 and zcyto25 proteins which are most closely related to interferon-.alpha. at the amino acid sequence level. The receptor for this protein family is a class II cytokine receptor. The prese...

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Bibliographische Detailangaben
Hauptverfasser:	KINDSVOGEL, WAYNE R, KLUCHER, KEVIN M, FOX, BRIAN A, TAFT, DAVID W, SHEPPARD, PAUL O
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to polynucleotide and polypeptide molecules for zcyto20, zcyto21, zcyto22, zcyto24 and zcyto25 proteins which are most closely related to interferon-.alpha. at the amino acid sequence level. The receptor for this protein family is a class II cytokine receptor. The present invention includes methods of reducing viral infections and increasing monocyte counts. The present invention also includes antibodies to the zcyto20 polypeptides, adn methods of producing the polynucleotides and polypeptides.