IMPROVED PROCESS FOR WATER SOLUBLE AZOLE COMPOUNDS

IMPROVED PROCESS FOR WATER SOLUBLE AZOLE COMPOUNDS

An improved process is provided for preparing water-soluble prodrugs of triazole antifungal compounds containing a secondary or tertiary hydroxyl group. More particularly, the improved process is directed toward preparatio n of water-soluble triazole antifungal compounds having the general formula (...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: KOLLA, LAXMA REDDY, PENDRI, YADAGIRI, MUELLER, RICHARD H, CONNOLLY, TIMOTHY PAUL, MATISKELLA, JOHN D, CHEN, CHUNG-PIN, PETSCH, DEJAH T
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:An improved process is provided for preparing water-soluble prodrugs of triazole antifungal compounds containing a secondary or tertiary hydroxyl group. More particularly, the improved process is directed toward preparatio n of water-soluble triazole antifungal compounds having the general formula (I ) wherein A is the non-hydroxy portion of a triazole antifungal compound of th e type containing a secondary or tertiary hydroxyl group and R and R1 are as defined in the specification.