PROCESS FOR FORMULATION OF ANTIBIOTIC COMPOUNDS

The present invention involves a process for preparing a stable final formulation product of a compound of formula (I) or its pharmaceutically acceptable salt, hydrate or solvate by incorporating a suitable carbon dioxide source to an unstable monosodium adduct of carbapenem antibiotic compound.

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Bibliographische Detailangaben
Hauptverfasser: TSINONTIDES, STELIOS C, HUNKE, WILLIAM A, AL-DEHNEH, ANTHONY, ILLIG, KATHLEEN J, REYNOLDS, SCOTT D, KANIKE, ANAND, PATEL, HIREN
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:The present invention involves a process for preparing a stable final formulation product of a compound of formula (I) or its pharmaceutically acceptable salt, hydrate or solvate by incorporating a suitable carbon dioxide source to an unstable monosodium adduct of carbapenem antibiotic compound.