N)-((S)-2-HYDROXY-3-METHYL-BUTYRYL-1-(L-ALANINYL)-(S)-1-AMINO-3-METHYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPIN-2-ONE DIHYDRATE AND ITS USE IN THE TREATMENT OF ALZHEIMER'S DISEASE

N)-((S)-2-HYDROXY-3-METHYL-BUTYRYL-1-(L-ALANINYL)-(S)-1-AMINO-3-METHYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPIN-2-ONE DIHYDRATE AND ITS USE IN THE TREATMENT OF ALZHEIMER'S DISEASE

The present invention provides crystalline (N)-((S)-2-hydroxy-3-methyl-butyryl)-1-(L-alaninyl)-(S)-1-amino-3-methyl-4,5,6,7-tetrahydro-2H-3-benzazepin-2-one dihydrate, compositions thereof, and methods for using the same, processes for making the same, and processes for making intermediates thereof.

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Bibliographische Detailangaben
Hauptverfasser: MCDANIEL, STACEY LEIGH, KOENIG, THOMAS MITCHELL, BUCCILLI, LYNNE ANN, ENGEL, GARY LOWELL, AIKINS, JAMES ABRAHAM, MITCHELL, DAVID, AUDIA, JAMES EDMUND
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The present invention provides crystalline (N)-((S)-2-hydroxy-3-methyl-butyryl)-1-(L-alaninyl)-(S)-1-amino-3-methyl-4,5,6,7-tetrahydro-2H-3-benzazepin-2-one dihydrate, compositions thereof, and methods for using the same, processes for making the same, and processes for making intermediates thereof.