MOLECULES FOR DISEASE DETECTION AND TREATMENT

The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT ) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. Th e i...

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Hauptverfasser: YAP, PIERRE E, CHEN, ALICE J, DAFFO, ABEL, HILLMAN, JENNIFER L, HARRIS, BERNARD, LIU, TOMMY F, JACKSON, STUART, WRIGHT, RACHEL J, PANZER, SCOTT R, INMAN, REBEKAH R, BRADLEY, DIANA L, AU, ALAN P, DAHL, CHRISTOPHER R, ROHATGI, SAMEER D, DUFOUR, GERARD E, MOMIYAMA, MONIKA G, DAVID, MARIE H, PERALTA, CAREYNA H, ALTUS, CHRISTINA M, YU, JIMMY Y, GIETZEN, DARRYL, MARWAHA, RAKESH, CHALUP, MICHAEL S, GERSTIN, EDWARD H., JR, ROSEBERRY, ANN M, LINCOLN, STEPHEN E, FLORES, VINCENT, JONES, ANISSA LEE, CHANG, SIMON C
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Sprache:eng ; fre
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Zusammenfassung:The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT ) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. Th e invention further provides for vectors and host cells containing mddt for th e expression of MDDT. The invention additionally provides for the use of isolated and purified MDDT to induce antibodies and to screen libraries of compounds and the use of anti-MDDT antibodies in diagnostic assays. Also provided are microarrays containing mddt and methods of use.