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The present invention provides purified secretory polynucleotides (sptm) and the polypeptides (SPTM) encoded by sptm. The invention also provides for the use of sptm, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cell...

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Hauptverfasser: YAP, PIERRE E, CHEN, ALICE J, DAFFO, ABEL, HILLMAN, JENNIFER L, HARRIS, BERNARD, LIU, TOMMY F, WRIGHT, RACHEL J, PANZER, SCOTT R, INMAN, REBEKAH R, BRADLEY, DIANA L, AU, ALAN P, DAHL, CHRISTOPHER R, ROHATGI, SAMEER D, DUFOUR, GERARD E, MOMIYAMA, MONIKA G, DAVID, MARIE H, PERALTA, CAREYNA H, ALTUS, CHRISTINA M, YU, JIMMY Y, GIETZEN, DARRYL, MARWAHA, RAKESH, CHALUP, MICHAEL S, ROSEBERRY, ANN M, GERSTIN, EDWARD H., JR, LINCOLN, STEPHEN E, STUART, JACKSON, FLORES, VINCENT, JONES, ANISSA LEE, CHANG, SIMON C
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention provides purified secretory polynucleotides (sptm) and the polypeptides (SPTM) encoded by sptm. The invention also provides for the use of sptm, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing sptm for the expression of SPTM. The invention additionally provides for the use of isolated and purified SPTM to induce antibodies and to screen libraries of compounds and the use of anti-SPTM antibodies in diagnostic assays. Also provided are microarrays containing sptm and methods of use.