METHOD FOR PRODUCING LAMOTRIGINE FROM ALPHA-OXO-2,3-DICHLOROPHENYL ACETAMIDINO-AMINOGUANIDINO HYDRAZONE BY RING CLOSURE REACTION

METHOD FOR PRODUCING LAMOTRIGINE FROM ALPHA-OXO-2,3-DICHLOROPHENYL ACETAMIDINO-AMINOGUANIDINO HYDRAZONE BY RING CLOSURE REACTION

The present invention relates to a method for producing 3,5-diamino-6-(2, 3- dichlorophenyl)-1,2,4-triazine (lamotrigine) by cyclization reaction from .alpha.-oxo-2,3- dichlorophenylacetamidino-aminoguanidino-hydrazone.

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Bibliographische Detailangaben
Hauptverfasser: GARACZI, SANDOR, LUKACS, FERENC, NYERGES, MIKLOS, ONDI, LEVENTE, SCHNEIDER, GEZA, MATE, ATTILA GERGELY, GEGO, CSABA LEHEL
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention relates to a method for producing 3,5-diamino-6-(2, 3- dichlorophenyl)-1,2,4-triazine (lamotrigine) by cyclization reaction from .alpha.-oxo-2,3- dichlorophenylacetamidino-aminoguanidino-hydrazone.