PRODUCTION METHOD OF 1-SUBSTITUTED-1,2,3-TRIAZOLE DERIVATIVES

PRODUCTION METHOD OF 1-SUBSTITUTED-1,2,3-TRIAZOLE DERIVATIVES

A method for producing (I) or (II), characterized in that (III) and (IV) are reacted (1) in a secondary or tertiary alcohol in the presence of a base or (2) in the absence of a base. The method can be employed for producing a 1- substituted-1,2,3-triazole compound having inhibitory action for tyrosi...

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Bibliographische Detailangaben
Hauptverfasser: TOMIMATSU, KIMINORI, IKEMOTO, TOMOMI, NISHIYAMA, HIROHIKO, ITO, TATSUYA, ISOGAMI, YASUSHI, SAWAI, YASUHIRO
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:A method for producing (I) or (II), characterized in that (III) and (IV) are reacted (1) in a secondary or tertiary alcohol in the presence of a base or (2) in the absence of a base. The method can be employed for producing a 1- substituted-1,2,3-triazole compound having inhibitory action for tyrosine kinase, in a high yield and with a simple and easy process, on a commercial scale.