DEXTROCHLORPHENIRAMINE TANNATE

The invention pertains to a novel composition comprising dextrochlorpheniramine tannate and to a method for preparing such tannate by reacting dextrochlorpheniramine free base at a temperature of about 60 to about 150.degree.C with tannic acid preferably neat or as an aqueous slurry containing about...

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Hauptverfasser: CHOPDEKAR, VILAS M, REDKAR, SHAM N, MELLOZZI, ANGELO R, ACHARI, RAJA G
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creator CHOPDEKAR, VILAS M
REDKAR, SHAM N
MELLOZZI, ANGELO R
ACHARI, RAJA G
description The invention pertains to a novel composition comprising dextrochlorpheniramine tannate and to a method for preparing such tannate by reacting dextrochlorpheniramine free base at a temperature of about 60 to about 150.degree.C with tannic acid preferably neat or as an aqueous slurry containing about 5 to about 30 wt.% water. The dextrochlorpheniramine tannate has extended release properties and is useful in pharmaceutical compositions as an antihistamine for human beings.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title DEXTROCHLORPHENIRAMINE TANNATE
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